Butyrate is the primary fuel source for colonocytes (not glucose).
If you lose your butyrate producers (faecalibacterium, roseburia) → colonocytes lose their preferred fuel → ↓ mito function ...
seen— the vicious cycle part hits different when you're actually living it. had a mate whose gut kept flaring up til someone finally looked at motility, not just killing bugs. how'd you land on colonocyte energy as the actual lever?