@nprofile1q... We built the prototype for the ESO ELT Adaptive Optics Wave-Front Real Time Computer on a handful of 48-core Epyc machines, with a stock FreeBSD kernel.
10Kx6K matrix, 700 times per second, with microsecond jitter.
Worked fine.
(Then we did it again again ten years later on a single server, with a stock Linux kernel, because they had standardized on that.)
See:
https://www.eso.org/sci/meetings/2023/RTC4AO/01_04_suarez_valles.pdfand
https://www.eso.org/sci/meetings/2023/RTC4AO/01_10_pedersen-kamp.pdf