@nprofile1q... @nprofile1q... @nprofile1q... The current guidelines exist because doctors can't do statistics. Even though it has been shown that the recommended dose should be higher, they haven't changed the guidelines.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4210929/
https://pmc.ncbi.nlm.nih.gov/articles/PMC4210929/