I wouldn't mind having some if someone made them filled with ground beef or something. But generally, we carnivores avoid them for the following nightshade anti-nutrients (and potential sprayed on glyphosate/poisons):
Tannins
Polyphenols
Flavonoids (e.g., quercetin, luteolin)
Oxalates
Dietary fiber (mineral-binding effect)
Capsaicin
Capsaicinoids
Glycoalkaloids (trace levels in edible parts)
Allergenic proteins
Biogenic amines (including histamine in processed/dried forms)