Yes and no, Blossom works for hosting the raw audio/video files but you can't really use it for the RSS feed itself because that needs to be a static URL and with Blossom if you make a change to the RSS feed (say you add a new episode) it changes the URL of the feed and breaks things.

There Is another Nostr spec 😅, two weeks ago https://github.com/nostr-protocol/nips/pull/2211/files