CoQ10 is fascinating to me. It does two things in the inner mitochondrial membrane which are crucial.
1. Shuttles electrons from Complex I/II → III (relating to energy production)
2. Lipid-soluble antioxidant sitting right where ROS are generated
↓ CoQ10 = ↓ ATP AND ↑ oxidative damage to cardiolipin and mtDNA simultaneously = so you get increased heteroplasmy rate
EAT MORE HEART.
Then you have one of the most widely distributed drugs in the world, statin, which inhibit HMG-CoA reductase. That is thesame pathway that produces CoQ10. I also believe research underestimates statin-induced fatigue and muscle issues, but is what it is.
1. Shuttles electrons from Complex I/II → III (relating to energy production)
2. Lipid-soluble antioxidant sitting right where ROS are generated
↓ CoQ10 = ↓ ATP AND ↑ oxidative damage to cardiolipin and mtDNA simultaneously = so you get increased heteroplasmy rate
EAT MORE HEART.
Then you have one of the most widely distributed drugs in the world, statin, which inhibit HMG-CoA reductase. That is thesame pathway that produces CoQ10. I also believe research underestimates statin-induced fatigue and muscle issues, but is what it is.